A very hard 'no'. I've been an entrepreneur the last 10 years and repetitively burnt myself out because an Engineering degree gave me the ability to learn any skill required and do it myself.
The perfectionism that often plagues Engineers and Scientists made me unhappy with the contributions of partners and work of contractors.
So did everything myself. Software development, sys admin, web-design, 2d and 3d graphics, marketing, the accounts, LLC compliance, e-commerce, customer support... I'm happy with the results, but it takes 2-3 times as long! By the time I'm ready to release a product, the market has changed.
I've been surviving (just) but I'd hate to think of my measly hourly rate compared to my first 10 years in the workforce. It does tempt me back sometimes.
The high-school leaver has no option but to chuck himself in the deep-end, to hire people and not think, "I can do better than that, why the hell am I paying for this."
I guess a degree may be a good fallback, but entrepreneurship tends to make one a jack-of-all-trades, master-of-none, so re-entering the workforce could be tricky given how specialized many industries have become.
I don't regret going to University because I would have been too stubborn to believe back then what 9 years has taught me. 4 years studying is a long time, I'd rather be out making mistakes, learning real people skills and have to release product regardless of how imperfect it is so I can eat, rather than having the luxury of taking my time.