What is your opinion on Provigil/modafinil? [closed]

I was perscribe Provigil about five years ago. I am resistant to anti-depressants and have major depressionl.The only thing left for me to do is have ECT, but four years ago at age 56 I had a stroke, respiratory failure, and went into a coma. My husband and my daughter watched as a priest gave me last rites. But, I got a miracle. I am all right.

But then the depression started again and was worse. I had to stop working as a teacher, a job I loved.

Finally, my psych. perscribe Provigil. It has made a tremendous change in my life. When I have a really bad spell, nothing works. But "normal" day are so hard and Provigil helps. Maybe it is risky, but I have a choice of never getting out of bed, having ECT which is risky because of my medical condition, or taking Provigil and only being sick one week a month.

People without Major Depression cannot understand how it feels. There is a website where people desribe their depression if anyone is interested: http//www.wingsofmadness.com/what-does depression-feel-like-446/comment446/ I think you could find it.

I have tried all or many of the remedies suggested over the years. Exercise makes me feel better until I am struke down again.

I am not yet willing to go to ECT, but even that may come.

To keep it on the topic of startups -- running a startup is more like a marathon than a sprint. If you (a) think you need extraordinary measures such as stimulants, or (b) that you're looking for short-term ways to get you through things, you're doing it all wrong. Don't look for drugs, look for serious flaws in your organization, your partners, your resources, or the scope of your initial startup work, something is really wrong. Do you really need money or partners who complement your skill set?

I think drugs like Provigil are the easy way out. And that always involves sacrificing something else, usually your health. I'm always extra suspicious when somebody is offering a drug to "fix" or "improve" me.

Right now I am working on improving my performance through changing my lifestyle. I switched to a healthy diet (went vegan, and I'm even considering raw foodism). I also started doing some exercise in the mornings. Physical activity has given me tremendous boosts in energy during the entire day. Note that I don't even do coffee anymore -- 20 push-ups do a much better job.

I have some provigil in the drawer next to me but have yet to take any: for me, naturally hacking brain chemistry with endorphins and sleep have proven to be much more important to creative productivity than raw horsepower.

My ideal day: 3 - 4 hours of concentrated effort in the morning, followed by short, intense interval training (e.g. crossfit.com), followed by another 5 - 6 hours of concentrated effort with a couple of hours of down time in the evening and a good night's sleep.

Invariably, I find that both in the morning after waking up and in the afternoon after the workout, there are unexpected realizations, connections, conclusions, insights.

I highly recommend a) endorphins and b) being more attuned to your own body (energy levels, concentration, attention span) over pharmaceuticals.

Exercise generates new neurons (1), generates anti-depressant hormones, and produces endorphins, which alleviate pain, induce euphoria, decrease appetite, improve cognitive functioning, and attach to the same receptors as opiates.

What's not to like about that? :-)

(1) http://serendip.brynmawr.edu/bb/neuro/neuro05/web2/mmcgovern.html

You're better off with a cup of walnuts and a good night sleep. As with @Neil Davidson's answer, Think about the Quality of your thinking time versus the pure Quantity.

We are not just talking about a cup of coffee to start your day or get you through a slow afternoon. The pharmaceuticals you are describing can be habit forming like coffee, but they're in a different ball game all together.

If you need modafinil to be productive in your line of work, maybe what you're doing isn't the right fit for you.

Taking medication day-in-and-day-out, just to get stuff done, isn't sustainable long term.

Funny you should ask, as just today I was reading a pretty interesting article on modafinil and related meds. Fascinating.

Whatever you do: consult your physician first. (Yes, you need a prescription, but I mean: consult a physican who knows you.) Some things aren't worth sacrificing, even for your dream.