(This is a reaction to some of the responses, more so than to the question itself.)
If you are so obsessed with your business that you have no time for your spouse and children, then, forgive me, but you have a problem that needs to be addressed. If the situation lasts only briefly, or pops up intermittently, that's normal; however, if "obsessed with work" is your normal mode, then you risk losing the people you love.
There is another dimension here as well. As an employee, I would not want to work for anybody who was willing to give up his family for his business. I want to work for an individual whose priorities I admire and share, not somebody I fear is going to expect me to make the same sacrifice he has made. So, in the end, your obsession can also hurt your business, as you alienate your employees even as you disengage from your family.
I'm not immune to this challenge; none of us are. But as human beings, and as "people-centered leaders," we owe it to ourselves and to our employees to keep our priorities straight. Starting a new business is hard. Starting a new family is much harder.