Yes, I've used them as my banker in one of my past businesses and now work with them on behalf of several clients who use their services. It depends on what you are looking for.
Strengths: Business banking security, international transactions, startup friendly offering fee free checking with no minimums for first year. They are hoping you get funded in the meantime. If you don't they may transition you to a small business account team after year one but fees are still only $25/mo. Client service executives are pretty accessible.
Weaknesses: Online banking interface is clunky, limited number of branches keeping 10a-3p hours (makes it tougher to deposit checks).
Depends: Offer client only networking forums and have pretty good connections with the key legal and VC firms in Silicon Valley which some find valuable and others not.
Net net: If you are a reasonably well funded scalable startup or a larger established business, they can be a good choice. If you are a bootstrap or lifestyle startup, you may be better off going with a commercial/consumer bank which tends to have better online banking and more branches and tend to be fee free.